1	Medical Murray, Inc. 1294 Barclay Blvd. Buffalo Grove, IL 60089 Developing Your Medical Device From Concept to Production
2	Background Founded in 1980 as Mechanical Engineering & Design Company New Ownership / Name April 1996 Transition to Medical Market Emphasis
3	Anticipate August 2005 Move In
4	Mission Statement
5	Market Needs We Serve Single source for any or all medical device development services from concept to production, including design, analysis, prototyping, testing, FDA submissions, pilot plant production, transfer to production Extensive experience with applications for disposables, durables and equipment Custom catheter design, development and production background No waiting to begin your project; rapid prototype development Miniaturization and Nanomolding™ We will be with you on every step of the development path to your destination
6	Our Customer Profiles
7	Our Products
8	Medical Murray People 24 full time engineers and technicians Educational background Mechanical Engineering Biomedical Engineering Quality Engineering Chemical Engineering Manufacturing Engineering Materials Science MBA
9	Capabilities
10	Engineering Tools 2-D CAD Autocad Cadkey 3-D Solid Modeling SolidWorks Pro Engineer Cadkey Analysis COSMOS (FEA) C-Mold (plastic flow)
11	Materials Experience Pebax Tecoflex Nylon Hytrel PET Silicone rubber PEEK Polysulfone Polyethylene Polyimide Titanium Polypropylene Noryl FEP, PTFE, PFA Teflon Polycarbonate Elastomers Thermoset epoxy, polyester Nitinol Stainless steel Hypotubes Shrink tubing Biodegradeable polymers
12	Process Equipment Braider (16 & 48 end) Vertical shrinker Balloon blower Hot die necker Injection molding machines (3) NanoInjection machines LIM (Silicone Rubber) injection molding Tube forming Ovens/Furnace Fluidized bed furnace Milling machines & lathes Clean room Wire rolling mill Pressure tester Tube flaring Pad printer
13	Process Experience Plastic processing Nano Injection molding Pressure forming (balloon blowing) Heat shrink bonding Extrusion Compression molding Insert molding Bonding, joining, blending Laminating Other processes Sonic welding Laser welding Miniature hole drilling Tip forming Machining Casting Sheet metal forming Pad printing
14	Strategic Partners Industrial Design Electronic / Software
15	Industrial Design
16	Electronic and Software Software Development Electronic Hardware Design
17	Medical Murray Markets Biotech Cardiology Dental Diabetes Dialysis Hearing Home Monitoring/Care Infusion Neurology Nanomolding Obesity Respiratory Therapy Spinal Sleep Apnea Syringe Safety Urology Vision
18	Medical Murray Disposable Device Experience Cardiovascular balloons High pressure drug injection catheter Esophageal balloons Ultrasonic imaging catheter Steerable catheter Stent Stent delivery catheters Guidewire Pressure sensors embedded in catheter RX exchange guides Stone retriever Pressure sensing guidewire Thermal-ablation Low temperature ablation Atherectomy catheter Guiding catheter Sensor delivery catheter
19	Catheters and Components Catheter and injection port assembly Braid example
20	Catheters and Components Catheter handle assembly Sensor Integration
21	Catheters and Components Custom balloon
22	Catheters and Components Ultrasonic Catheter assembly Ultrasonic sensor
23	Catheters and Components Catheter assembly Catheter kit
24	Unique Patented Technology Sesame NanoMolding Machine .01 to 80 mm³parts Silicone rubber or thermoplastic Insert molding
25	NanoMolding Examples Bioabsorbable implants Silicone Rubber – polycarbonate molding
26	Micro Surgical Component Tube ID = 90 micron OD = 280 micron Length = 1.8 mm Volume = 0.1 mm³ Weight = .0001 g Material - TPE
27	Micro Implant Implant ID = .11 mm OD ~ .60 mm Length = 1 mm Volume = 0.4 mm Material - Silicone
28	Catheter – Tip Transition
29	Dental Equipment Examples Light cure gun Tooth manifold Composite delivery Syringe heater Multiple dental fluid dispenser
30	Dental Equipment Examples
31	Bio-Tech Equipment Micro-array robotic handling system Surgery control module Hybridization station Dialysis fluidic system Infusion pump
32	Surgery Control Module
33	Production Prototype Documentation Design for Manufacturability Validation Fixtures & Tools Product Reliability Testing Released Documentation
34	Regulatory Compliance Operating under and pursuing ISO 13485 (anticipate certification June 2005) FDA Registered UL, CE Mark, FDA 510K & PMA
35	Clean Room Assembly Low to medium volume production Braiding Bonding Welding Molding Assembly Testing Sensor wiring
36	Project Philosophy Understand the Project Requirements Understand the Necessary Steps to Successful Completion Address Project Risks Early Clear Communication with Partners and Clients Execute Each Step Decisively Test for Successful Completion
37	Exactly What Medical Murray Can Do For You Research Design Model Develop Test Miniaturize FDA Submissions Biocompatibility * Sterilization * Packaging design Early stage production Produce or transfer * Manage services by others
38	Devices and Systems Developed By Medial Murray Catheters Stents Embolic Filters Stent Placement Artificial Discs Biopsy Ultrasonic Imaging Catheter Stone Retriever Catheters with embedded elec. Nanomolding Isotope Delivery Systems Balloon Blower Tube Flaring Tube Forming Ultrasonic Guide Catheter Sensing Guidewire Hemodialysis Light Curing Corseting Drug Delivery Multiple Fluid Dispensing DNA Hybridization
39	Why Consider Medical Murray for your Medical Device? Single source from concept to production No hidden processes or technologies More choices without interruption to your regular business activities We have a unique combination of project experience, people, facilities, equipment, and sense of urgency to competitively deliver “your desired results”